ACS DEPARTMENT OF CARDIOVASCULAR RESEARCH
Introduction
The ACS Research Department is an internationally
reputed state-of-the-art cardiovascular research site with an established,
high-volume, quality program, serving a patient population of over 150,000
nationwide.
Leading-edge research has been a part of Advanced
Cardiac Specialists since its inception in 1991. Most of the cardiologists
and internists at ACS are actively involved in the research activities.
The research program is headed by a cardiologist as medical director, and
has a well-established infrastructure employing a research director,
research nurses and clinical coordinators. With a full-fledged specialized
staff dedicated to patient care, our activities keep ACS in the forefront
of medical science and at the leading edge of technology.
Registry
& Original Research
Based on meticulous data collection, the research
department maintains several registries including Coronary Interventional
(Angioplasties / Stents) Registry, Heart Failure Registry and Cardiac
Rehabilitation Registry.
The ACS Coronary Interventional (Angioplasty) Registry
is a meticulous record of all coronary interventional procedures performed
at the ACS – Outpatient Treatment Center (ACS-OTC) since it opened in
December 1993 (currently part of the Cardiovascular Center at Mesa General
Hospital). This includes balloon angioplasties, laser angioplasties,
directional atherectomies, rotational atherectomies and intracoronary
stents. The database is updated regularly and serves as a valuable point
of reference for vital information on patient outcomes, including
immediate procedural success and long-term clinical outcomes. We also
conduct regular "meta-analyses" comparing the data from the
registry with outcomes from landmark international and national trials.
This provides a scientific and objective way of ensuring quality control.
The Registry currently consists of over 8,500 patients. One-year
follow-up is more than 95% complete at all times.
In the last five years, we have added other registries,
including the Heart Failure Registry (412 patients), the Cardiac
Rehabilitation Registry (3,000 patients) and a Registry on PTA of Dialysis
Access Site Fistulas.
Scientific
Research Presentations & Publications
This data has served us well in terms of monitoring and
modifying the quality of care we provide to our patients. It has also
served the international medical / scientific community well and has
resulted in 86 presentations in the past eight years, at
international scientific conferences in the U.S., Canada, Europe and Asia.
The scientific forums have included the American College of Cardiology,
American Heart Association, Society of Cardiac Angiography &
Intervention, European Society of Cardiology, Heart Failure Society of
America and the World Congress of Cardiology.
Our presentation on "Stenting versus
Balloon Angioplasty in Acute Myocardial Infarction" was
included in the "Featured Research" section
of the American Heart Association Scientific Sessions held in Orlando,
Florida in November 1997. Our paper on "Stenting the Coronary Vessel
in Diabetics" was selected as a "Special
Interest" presentation at the XXIst Scientific Congress of
the European Society of Cardiology held in Barcelona, Spain, in August
1999. ACS’ contributions to scientific research were further recognized
when we were invited to present our experience in the treatment of
Coronary Heart Disease at the First World Congress of Cardiology in Prague
in September 1997, and the Second World Congress of Cardiology in
Florence, Italy, in October 1998. Our abstracts/papers have also been
published in internationally indexed medical journals. In the last three
years alone, ACS had over 25 original scientific research papers at
international cardiology conventions. These were recognized by our peers
as path-breaking and stimulated exceptional interest and informative
interaction.
Special
Recognitions & Awards
-
Recognized as one of 20 "elite
sites" for Pilot Studies and Phase I clinical trials of
new interventional devices, 2000 - 2001.
-
Independent IDE (Investigational Device Evaluation)
registration with the FDA, 1994 - 2000.
-
Received accreditation by the National Institutes
of Health for research conducted in interventional cardiology
at the ACS-OTC, 2000 to present.
-
Featured research presentation at the 70th
Scientific Sessions of American Heart Association in Orlando, Florida
1997.
-
Paper selected as of special public interest at the
20th Congress of the European Society of Cardiology in
Vienna, Austria, 1998.
ACS
Clinical Trials Research Program
The ACS research program is one of the few programs of
this caliber, available in the Southwest. ACS has been an active and leading
participant in 106 international, multicenter trials monitored by the
FDA. These trials specifically target some of our sickest patients who have
complex coronary heart disease, left ventricular dysfunction, heart failure
and arrhythmias. Thus, patients benefit from a wide range of new and
advanced medications and biotechnical advances that are not otherwise
available commercially or at other physicians’ offices / hospitals, at no
additional cost to the patient.
Currently, nearly 88
patients are being cared for through our research
efforts, and we have 12 research
trials in progress. This includes patients
from across several states throughout the U.S.
Research
Affiliations
-
American Black Cardiologists Association (ABC)
-
Cardiovascular Clinical Research Center, New York
University School of Medicine, New York
-
Cardiovascular Research Foundation, NY-Presbyterian
Hospital / Columbia University Medical Center
-
Cleveland Clinic Cardiovascular Coordinating Center
(C), Cleveland Clinic Foundation
-
Duke Clinical Research Institute (DCRI), Duke
University Medical Center
-
Harvard Clinical Research Institute (HCRI), Boston,
Massachusetts
-
Harvard Medical School / Brigham and Women’s
Hospital
-
Jewish General Hospital / McGill University,
Montreal, Canada
-
Mayo Physicians’ Alliance for Cardiovascular Trials
(M-PACT)
-
Mount Sinai Medical Center, Miami, Florida
-
National Institutes of Health (NIH)
-
National Heart, Lung, Blood Institute (NHLBI)
-
New Approaches to Coronary Intervention (NACI),
University of Pittsburgh
-
St. Luke – Roosevelt Hospital Center, New York
-
University of Arkansas
-
William Beaumont Hospital, University of Michigan.
Managing
Congestive Heart Failure: ACS Comprehensive Heart Failure Program
ACS has an established reputation as a leader in Heart
Failure Research in the state of Arizona. ACS has been a leading participant
in the Southwest for a wide spectrum of FDA-approved heart failure trials.
ACS’ experience with these trials has been extremely
gratifying and is due to the combined strengths of dedicated expert care,
close follow ups, personalized attention, as well as new medical
breakthroughs. Thus, ACS is in a unique position to provide comprehensive
and state-of-the-art healthcare to a large volume of patients with
congestive heart failure, combining the strengths of primary care with
leading-edge cardiology, in a cost-effective and readily accessible way.
Additionally, our close affiliation with major cardiovascular university
medical centers ensures that each patient will receive the best and most
comprehensive medical expertise, in the most efficient and personalized
manner.
Keeping this in mind, we run a dedicated Heart Failure
Clinic at our Gilbert location. This helps ensure that leading-edge care is
available to the maximum number of patients with Congestive Heart Failure (CHF),
in an effort to improve their survival and quality of life. (Please see
Section on: Heart Failure.)
What's New in Research
-
New drug-eluting stent trials in coronary artery
disease
-
New drug-eluting stent trials in vascular artery
disease
-
New drug therapies in the treatment of coronary heart
disease
-
Transcatheter (non-surgical) closure of patent
foramen ovale ("hole in the heart") in patients with
unexplained strokes / ministrokes
-
Biventricular pacemakers in advanced heart failure
-
New drug therapies in heart failure
-
New technologies (e.g. radiofrequency ablation
therapy) in the treatment of heart rhythm disorders
-
New devices implanted in the left atrial appendage,
to prevent strokes in patients with atrial fibrillation
-
Newer models of defibrillators (ICDs) and pacemakers
-
New endoluminal stent grafts in the treatment of
aortic aneurysms
-
Carotid artery stent trials.
ACS is also looking at partnering with leading-edge
molecular biologists to study atherosclerosis and gene manipulation in
animal models. This may have important implications for the management and
even cure of atherosclerosis in the future.
Information for
Patients & Referring Physicians
If you are suffering from heart failure and are
interested in learning more about your clinical condition; or, would like
more information regarding opportunities for participation in research,
please contact the Research Department at (480) 545-1847, or e-mail us at bobbie.boyd@acs-im.com.
If you are a primary care physician or a cardiologist and
are interested in obtaining additional information on one or more trials, or
if you have a patient who you feel may benefit from participation in a heart
failure trial, please contact the Research Department at (480) 545-1847, or
e-mail us at bobbie.boyd@acs-im.com. |